Pandol Night

About Panadol Night and how it works

This medicine helps relieve mild to moderate pain such as headache, migraine, neuralgia, backache, toothache, period pain; and rheumatic and muscle pain. It is helpful if the pain disturbs your sleep. The main ingredients in this medicine are paracetamol and diphenhydramine which work together to help relieve pain and aid a restful sleep. Paracetamol is a pain killer and helps relieve pain and fever. Diphenhydramine is an antihistamine which works by blocking the effects of histamine and causes drowsiness.
This medicine is available in the form tablets that are taken by mouth. You should take this medicine 20 minutes before going to bed.
This medicine contains paracetamol. If you are taking other medicines that contain paracetamol you must make sure that you do not take more than the recommended daily dose of paracetamol. You should also avoid taking other medicines that make you drowsy.
Do not take this medicine continuously for more than seven nights.
Consult your doctor if you have a persistent headache or if your symptoms do not improve after taking this medicine for seven days, or if they get worse during treatment with this medicine.

Before using Panadol Night

This medicine may not be suitable for everyone and some people must never have it. Check the leaflet that comes with your medicine to make sure that the medicine is suitable before having it.
Always get advice from a healthcare professional before taking this medicine if:

• you are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
• this medicine is for a child under 12 years of age
• you are elderly
• you have liver problems
• you have kidney problems
• you have pyloroduodenal obstruction
• you have porphyria
• you have heart and circulation problems
• you have asthma, bronchitis, COPD or lung problems
• you have myasthenia gravis
• you have epilepsy or another condition that makes you prone to seizures
• you have closed-angle glaucoma
• you have an enlarged prostate gland
• you have urinary retention
• you have galactose intolerance
• you have Lapp lactase deficiency
• you have glucose-galactose malabsorption
• you are taking other medicines that contain paracetamol

Medicines interactions
If you are taking more than one medicine they may interact with each other. Before taking this medicine consult your doctor or pharmacist if you are taking or have recently taken any other medicines including vitamins supplements and herbal or complementary preparations.
The following medicines may interact with this medicine:

• other medicines that contain paracetamol
• cough and cold medicines
• other antihistamines including preparations that are applied on the skin
• metoclopramide
• domperidone
• cholestyramine
• anticoagulants such as warfarin or other coumarins
• monoamine oxidase inhibitors - you should not use this medicine within two weeks of stopping a monoamine oxidase inhibitor or while you are taking one
• central nervous system depressants such as tranquilisers, hypnotics and anxiolytics
• antimuscarinic medicines such as atropine or tricyclic antidepressants
• medicines that are metabolised by cytochrome p450 such as metoprolol and venlafaxine

Possible side effects of Panadol Night

Most medicines can cause some side-effects but not everyone having the same medicine will get the same side-effects.
The following side-effects have been associated with people taking this medicine:

• hypersensitivity reactions including anaphylaxis, skin rashes, angioedema, urticaria, breathing difficulties, Stevens-Johnson syndrome and toxic epidermal necrolysis
• bronchospasm
• liver problems
• tiredness
• confusion
• paradoxical excitation including feelings of increased energy, nervousness and restlessness
• dizziness
• concentration problems
• unsteadiness
• convulsions
• headache
• blood and bone marrow problems
• drowsiness or sedation
• blurred vision
• faster heart rate
• palpitations
• thickening of bronchial secretions
• dry mouth
• gastrointestinal disturbances including nausea and vomiting
• muscle twitching
• urinary retention
• urinary difficulties
• difficulty in co-ordinating movement
• pins and needles sensations

Pregnancy and breast-feeding

If you are trying to become pregnant or are pregnant you should seek medical advice before taking this medicine. Do not take this medicine if you are breast-feeding.

Other important information

Make sure that you read the leaflet that comes with your medicine to check what dose you should take and if there is anything that you need to do if you take more than the recommended dose. If you are in any doubt about whether this medicine is suitable for you, speak to your doctor or pharmacist.
Seek immediate medical advice if you accidentally take an extra dose of this medicine even if you feel well.
This medicine may affect your ability to drive or operate machinery. If this medicine affects you, you should not drive or operate machinery.
This medicine may interact with alcohol. It is best to avoid alcoholic drinks while you are taking this medicine.
Keep all medicines out of the sight and reach of children.